A new study published in the European Journal of Pain last month found that both macro and micro doses of classic psychedelics — LSD, psilocybin, DMT, mescaline — led to better pain relief compared to conventional medication in volunteers surveyed.
Four of those five, with sciatica being the exception, were reported to be relieved by psychedelics on the dosage day, as well as 1-3 days after, with a few even reporting pain relief beyond the third day.
While this is a breakthrough, it’s important to note that more research is needed to fully harness the potential of psychedelics in pain relief.